Research Core Facilities
In support of its research and educational activities, Dana-Farber Cancer Institute has developed and centrally maintains a variety of core facilities and service functions to support its research and educational activities, including:
AIDS Drug Screening
Services offered include screening compounds for toxicity and anti-HIV activity on various cell lines and human peripheral blood cells. Compounds can be screened against a variety of viruses, including clinical isolates and drug resistant strains.
Location: Jimmy Fund 7
Contact E-mail: Joseph_Sodroski@dfci.harvard.edu
Baruj Benacerraf Library
The Baruj Benacerraf Library provides journals and books, photocopying, interlibrary loans, database searching and training in database searching, as well as public access to computers. The library is open from 9 a.m. to 5 p.m., Monday through Friday.
Location: Smith 314
Contact E-mail: Christine_Fleuriel@dfci.harvard.edu
Biohazard Containment Core
This core provides technical support in the preparation and propagation of viral stock and cell lines. It also provides technical support in phenotypic characterization of virus variants.
Location: Jimmy Fund 7
Phone: (617) 632-3012
BioInformatics
BioInformatics provides the latest available computational molecular biology tools, user accounts on our system, and training and support of these tools for our user community.
Location: Jimmy Fund 220
Contact E-mail: Thomas_Graf@dfci.harvard.edu
Biostatistics Core
Biostatistics provides biostatistical expertise for the planning, conduct, analysis, reporting, and grant preparation of clinical, laboratory, and population-based studies.
Location: Mayer 232
Contact E-mail: Rebecca_Gelman@dfci.harvard.edu
The Connell and O'Reilly Families Cell Manipulation Core
The Connell and O'Reilly Families Cell Manipulation Core provides cell processing for patients enrolled in clinical research protocols. A variety of innovative cell manipulation techniques are currently available, including processing of hematopoietic stem cells, preparation of tumor vaccines, and generation of T cells for adoptive immunotherapy.
Location: Dana 530
Contact E-mail: Jerome_Ritz@dfci.harvard.edu
Flow Cytometry Core Lab
The Flow Cytometry Core supports Research at Dana-Farber. Our services include three high-speed cell sorters, four tabletop analyzers that can be used 24/7, and a BioPlex 200. For more information, please visit our Web site at flowlab.dfci.harvard.edu.
Location: Jimmy Fund 415
Contact E-mail: Peter_Schow@dfci.harvard.edu
Medical Arts
Medical Arts provides complete computer and custom graphics and photography services, including all needs for scientific publications and presentations, color and black and white prints, slides, full posters and titles, brochures, flyers, adds, and special events photography.
Location: Jimmy Fund 833
Contact E-mail: Minou_Modabber@dfci.harvard.edu
Microarray Core Facility
Starting with RNA provided by investigators, the facility carries out expression profiling using oligonucleotide microarrays. Genome-wide SNP analysis and resequencing analysis using oligonnucleotide microarrays are also services of the laboratory.
Location: Smith 11
Contact E-mail: Edward_Fox@dfci.harvard.edu
Molecular Biology Core Facilities
The Molecular Biology Core Facilities offers a full suite of molecular biology services to the Institute as well as the surrounding Harvard Medical School. These services include automated DNA sequencing, DNA and peptide synthesis, protein sequencing, amino acid analysis, BIAcore protein ligand assays, and mass spectrometry.
Location: 21-27 Burlington Ave, 4th floor
Contact E-mail: Paul_Morrison@dfci.harvard.edu
Molecular Biology Core Facilities Web site
Monoclonal Antibody Core
The Monoclonal Antibody Core was created to provide consistent, economical, and high quality protein and antibody generation and production, as well as to provide antibody-related products and services to support basic research and clinical projects.
Location: 21-27 Burlington Ave., 4th floor
Contact Core Director: James_DeCaprio@dfci.harvard.edu
Contact Co-Director: Laura_Corral@dfci.harvard.edu
DF/HCC Monoclonal Antibody Web site
The Shannon McCormack Molecular Diagnostics Laboratory
The Shannon McCormack Molecular Diagnostics Laboratory is a project-driven facility that provides specimen processing and tracking, DNA sequencing, microsatellite and SNP analyses, quantitative PCR, as well as other services, to analyze genes that are, or may be, involved in the etiology of cancer.These services are also available for clinical trials.
Location: 21-27 Burlington Ave, 4th floor
Contact E-mail: Edward_Fox@dfci.harvard.edu